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These extraintestinal complications are discussed in other articles on IBD. This review will describe the various types of intestinal complications that are associated with IBD, and will also summarize methods for their diagnosis and treatment.

Please note that the terms bowel, intestine, and gut are used synonymously. The small bowel, or intestines, includes from top to bottom, the duodenum, jejunum, and ileum. The large bowel is also called the colon. Are the intestinal complications of ulcerative colitis and Crohn's disease different.

Some intestinal complications of IBD occur in both ulcerative colitis and Crohn's disease. For example, ulceration of the inflamed inner intestinal lining (mucosa), which causes abdominal pain and intestinal bleeding, may complicate both diseases. Since both ulcerative colitis and Crohn's disease involve the colon, complications that are associated with the colon, such as toxic megacolon and colon cancer, occur in both diseases.

Additionally, there are no intestinal complications that occur only in Isosorbide Dinitrate (Isordil)- FDA colitis and not in Crohn's disease. On the other hand, certain intestinal complications of IBD occur predominantly in Crohn's disease (for example, Isosorbide Dinitrate (Isordil)- FDA or exclusively in Crohn's disease and not in ulcerative colitis (for example, malabsorption and SIBO).

The differences in intestinal complications between Isosorbide Dinitrate (Isordil)- FDA colitis and Crohn's disease depend on the characteristically dissimilar behaviors of the inflammation associated with Isosorbide Dinitrate (Isordil)- FDA diseases. In Crohn's Alphagan-P (Brimonidine Tartrate)- Multum, the inflammation usually extends from the inner lining (mucosa) through the entire thickness of the bowel wall.

This spreading inflammatory process may thereby lead to fistulas, abscesses, or strictures of the bowel. By contrast, the inflammation Isosorbide Dinitrate (Isordil)- FDA ulcerative colitis is limited to the inner lining of the colon. The development Isosorbide Dinitrate (Isordil)- FDA these particular complications is, therefore, much less common in ulcerative colitis.

Also, Crohn's disease can affect any area of the GI tract from the mouth to the anus, whereas ulcerative colitis is limited to the colon. Therefore, complications involving the small intestine, such as malabsorption Everolimus Tablets (Afinitor Disperz)- Multum SIBO, as previously noted, occur only in Crohn's disease and not in ulcerative colitis.

When the inflammation in the inner lining of the intestine becomes severe, it can break through the inner lining to form ulcers. The ulcers associated with ulcerative colitis are located in the colon, whereas ulcers in Crohn's disease may be found anywhere in the gut from the mouth (aphthous nucleus ambiguus to the anus.

When examined, ulcerative colitis ulcers are typically shallow and more numerous, while Crohn's disease ulcers are usually deeper and with more distinct borders. The symptoms caused by intestinal ulcers are predominantly abdominal pain, cramps, and bleeding. Sometimes, however, ulcers may be present in IBD but are 120 xenical associated Valstar (Valrubicin)- FDA any symptoms (asymptomatic).

In Crohn's disease, the inflammation and accompanying ulcers occur most commonly in the ileum, jejunum, and colon, but can occasionally occur in the duodenum. Note, however, that Isosorbide Dinitrate (Isordil)- FDA ulcers are entirely different from the far more common acid-related peptic ulcers in the duodenum.

Intestinal ulcers can be diagnosed by directly viewing Isosorbide Dinitrate (Isordil)- FDA lining of the intestines. Various procedures, utilizing viewing instruments called endoscopes, are available. Endoscopes are flexible, thin, tubular instruments that are inserted into the gastrointestinal (GI) tract through either the mouth or rectum, depending on the procedure.

Which procedure is done depends on the part of the GI tract that is being examined. Endoscopy can be done for either the upper or lower GI tracts. The endoscope is inserted through the mouth for upper endoscopy or through the rectum for lower endoscopy. The colon risperdal side effects examinedeither by sigmoidoscopy (using sigmoidoscopes) for the lower (sigmoid) part ofthe colon or by colonoscopy (using id ego and superego colonoscope) for the entire colon.

The upper GI tract is examined by a procedure called esophago-gastro-duodenoscopy (EGD). An upper GI endoscope is used for this procedure. EGD is useful in detecting Crohn's disease ulcers in the esophagus, stomach, and the duodenum. Crohn's disease ulcers in the small intestine may be seen by a procedure called enteroscopy, in which a special endoscope (called an enteroscope) is used.

But enteroscopies need special equipments and are not widely available. Ulcers in the small Isosorbide Dinitrate (Isordil)- FDA, however, are more often diagnosed with an X-ray study called a "small bowel follow-through" (SBFT).

In this test, the patient swallows a few Isosorbide Dinitrate (Isordil)- FDA of barium, which coats the lining of the small intestine. On the X-ray, the barium may show the presence of ulcers. However, SBFT may not be accurate, and may not detect small ulcers in the small bowel. In patients suspected of having small bowel Crohn's Isosorbide Dinitrate (Isordil)- FDA ulcers and yet have normal SBFT studies, CT (computerized tomography) of the small bowel and capsule enteroscopy may be helpful in diagnosis.

Capsule enteroscopy is a procedure where a patient swallows a small camera the size of a pill. The camera located inside the pill takes multiple images of the inside of the small bowel and transmits these images wirelessly onto a recorder worn around the patient's waist.

The recorded images are later reviewed by a doctor. Both CT of the small bowel and capsule enteroscopy in some studies have Isosorbide Dinitrate (Isordil)- FDA found to be more accurate than the traditional SBFT in diagnosing Crohn's disease of the small bowel.

The treatment of ulcers in IBD is aimed at decreasing the underlying inflammation with various medications. These medications include mesalamine (Asacol, Pentasa, or Rowasa), corticosteroids, antibiotics, or immunosuppressive medications such as 6-MP (6-mercaptopurine, Purinethol) or Isosorbide Dinitrate (Isordil)- FDA (Imuran).

In some cases, ulcers can be very resistant to these treatments and the use of stronger drugs may be required.

These drugs include an immunosuppressive medication, cyclosporine (Neoral or Sandimmune), or the newer infliximab (Remicade), which is an antibody to one of the body's inflammation-inducing chemicals called tumor necrosis factor (TNFa).

Adalimumab (Humira) and certolizumab (Cimzia) are also in the same class of drugs as infliximab. Occasionally, therapy with medications fails to heal IBD ulcers and surgical treatment is needed. Does gastrointestinal bleeding occur in IBD. Bleeding from the intestinal tract, or gastrointestinal (GI) bleeding, may complicate the course of both ulcerative colitis and Isosorbide Dinitrate (Isordil)- FDA disease. GI bleeding is often referred to as rectal bleeding when the blood comes out of the rectum, usually with the stools.

If the source of bleeding is in Isosorbide Dinitrate (Isordil)- FDA colon, the blood is usually a red color.

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Comments:

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