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Su PH, Chen JY, Pregnancy risk CM, Huang TC, Lee HS. Comparison of ibuprofen and indomethacin therapy for pregnancy risk ductus arteriosus in preterm infants. Van Overmeire B, Follens I, Hartmann S, Creten WL, Van Acker KJ. Treatment of patent ductus arteriosus with ibuprofen. Arch Dis Child Fetal Neonatal Ed. Su BH, Lin HC, Chiu HY, Hsieh HY, Chen HH, Tsai YC. Comparison of ibuprofen and indomethacin for early-targeted treatment of patent ductus arteriosus in extremely premature infants: a randomised controlled trial.

Ohlsson A, Shah SS. Ohlsson A, Walia R, Shah S. Shah SS, Ohlsson A. Non-steroid anti-inflammatory drugs in the treatment of patent pregnancy risk arteriosus in European newborns. Grosser T, Smyth E, Garret A, FitzGerald A. In: Brunton Pregnancy risk, Chabner B, Knollman B, editors. Young TE, Mangum B. Neofax: A Manual of Drugs Used in Neonatal Care. Neonatal Formulary: Drug Use in Pregnancy and the First Year of Life. Clinical pharmacology of indomethacin in preterm infants: implications in patent ductus arteriosus closure.

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Learn more Favored Authors We offer real benefits to our authors, including fast-track processing of papers. Learn more Promotional Article Monitoring Register your specific pregnancy risk and specific drugs pregnancy risk interest and we will match the information you provide to articles from pregnancy risk extensive database and email PDF copies to you promptly. S59376 Checked for plagiarism Yes Review pregnancy risk Single anonymous peer review Peer reviewer comments 2 Gian Maria Pacifici Medical School, Department of Translational Research and New Technologies in Medicine and Surgery, Section of Pharmacology, University of Pisa, Pisa, Italy Objective: The objective of this study was to evaluate the extent of renal adverse effects caused by ibuprofen or indomethacin in order to choose the safer drug to administer to preterm infants.

Keywords: ibuprofen, indomethacin, patent-ductus-arteriosus, renal-side-effects Introduction Ibuprofen and indomethacin are nonselective inhibitors of cyclooxygenase (nsCOX), are potent inhibitors of prostaglandin E2 synthesis, Kedbumin (Albumin (Human) U.S.P.] Sterile, Aqueous Solution for Single Dose Intravenous Administrati are lupus erythematosus systemic to close the patent ductus arteriosus (PDA).

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Table 3 Number of preterm infants with oliguria following the administration of ibuprofen or indomethacin for the closure of the patent ductus arteriosusNotes: aInfants with a body weight 7 days, the initial indomethacin dose was 0. All our Products are manufactured in WHO GMP, ISO 9001 Approved Manufacturing Facilities.

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